models

72

2.4.4.1 The multi-statistics multivariate model

73

2.4.4.2 The multi-replicate multivariate model

74

ary

75

se Cleavage Pattern Discovery

77

biology question — protease cleavage

78

e linear discriminant analysis algorithm

79

.1 The definition and working principle of LDA

80

.2 The projection direction optimisation

81

.3 The formulation of LDA

84

.4 Making decision using the Bayes rule for a LDA model

87

.5 The R function for LDA

89

e other analytic discriminant analysis algorithms

93

.1 The quadratic discriminant analysis algorithm

93

.2 The Naïve Bayes algorithm

95

.3 The logistic regression algorithm

95

.4 The Bayesian linear discriminant analysis

97

aluation and generalisation of a supervised machine learning

odel

98

.1 Confusion matrix

98

.2 Receiver operating characteristic analysis

101

.3 Generalisation

106

ample

109

nlinear algorithms

114

.1 Multi-layer perceptron

115

3.6.1.1 The structure of MLP

115

3.6.1.2 The learning mechanism of MLP

117

3.6.1.3 From SLP (LDA) to MLP

119

3.6.1.4 The R packages for MLP

120

.2 Radial basis function neural network

122

.3 The bio-basis function neural network algorithm

124

3.6.3.1 The bio-basis function neural network algorithm

126

3.6.3.2 The Bayesian BBFNN algorithm

128

3.6.3.3 The orthogonal kernel machine

131

.4 The support vector machine algorithm

132

.5 The relevance vector machine algorithm

137

.6 Deep neural network

139

.7 Inductive learning

141